I use twitter primarily as my news reader and I follow about a 100+ users.

I wrote this chrome extension to re-order by twitter timeline so that I don't miss out on the important stuff and to tune out users who tweet a lot but I still don't want to mute them. It's currently not open source, but if there's sufficient interest, I'll cleanup & put it here : https://github.com/hackybird/chrome . All data is stored locally in your browser.

Usage : Just load a timeline & click the extension. No signup needed.

Features :

- Sort any twitter timeline (or search) by retweets & likes

- Assign weights to users to change their tweets' order (e.g. someone whose tweets are important to you but they don't gather enough retweets/likes & may get buried down).

- Mark tweets as "read"