Also, I see the gzip support, but you should also be able to send the gzipped file as-is (with the right content-length, etc) if the Vary headers from the client support it.
Edit: I don't see it figuring out, and sending, the right Content-type header. Or is that functionality that comes with the base class you're using to serve http?
No sendfile() support as of now but seems like a good addition as it probably would speed up the caching.
The base HTTP server class sends only the timestamp and version and doesn't send the Content-type header. Python's SimpleHTTPServer[1] does this in a simple-enough manner and it would make a good pull-request :)
[1] https://github.com/enthought/Python-2.7.3/blob/master/Lib/Si...