I am using it for the site http://www.quotezuki.com. It has been working out pretty well, and Roberto the main developer is very good about helping people out on the mailing list.

I use it with nginx since the uwsgi module is included in nginx starting at 0.8.40.

I should point out though that if you are using uwsgi_pass within your nginx config, you will have to use uwsgi_* configuration variables instead of fastcgi_* variables for things like read_timeout.