If anyone is interested in a talk by one of the authors (Kevin Strange), he goes into the history of the compound here: https://www.youtube.com/watch?v=6aAr5pKW9Dw
For progress on similar lines of tech, this is a good site: https://www.lifespan.io/the-rejuvenation-roadmap/
Also paper explained that the drug had been applied in Phase 1 clinical trials with humans as a treatment for diabetes and obesity.
"Importantly, the doses we have shown to be effective in stimulating tissue regeneration are 5–50-times lower than the maximum well-tolerated human dose."
And doesn't get patented to hell with insane pricing.
It's been a cause of tension in trade negotiations.
Insulin is still patented in US even though it was invented in Canada.
Color were brighter after the first few days. Not psychedelic brighter but bluer blues, greener greens. What I felt was reminiscent of that child-like awe in experiences along with remembering instances of those awe-filled moments I had as a child.
Looking at the sky and watching the nature (which is something I hadn't been doing in years) made think "I'm lucky to be able to observe this". Looking at the sky and watching the way clouds move brought back flashbacks of probably the last time I had done that as a kid.
Very interesting chemical indeed. I believe it has a lot of potential.
After using up my supply, there was no withdrawal or crash. I guess the color enhancement went away gradually over a few months. However I could argue I got permanent memory enhancement from it. I have no data to support it but I became the kind of person that can remember the most obscure things and follow really long chains of connotations. And if you asked me, I wasn't like that before experimenting with NSI-189.
But that being said, I even tried Cerebrolysin months before that for nootropic exploration. So for all we know, the memory enhancement stems from that. In hindsight, I must have been very daring to have injected myself with peptides purified from pig brains. :)
Yes it is. And the pharma industry is pretty butthurt about it.
https://blogs.wsj.com/indiarealtime/2015/03/19/inside-india-...
https://www.forbes.com/sites/johnlamattina/2013/04/08/indias...
>India’s law sets a higher bar for protection than in some other countries, limiting the ability of companies to get patents for new versions of drugs whose active ingredients were previously known unless they can show significant therapeutic benefit.
It's not ignoring patents, it's setting a high bar for them. You can't rehash old medicine and patent them.