Covid vaccine passes phase 1 human trial(thelancet.com) |
Covid vaccine passes phase 1 human trial(thelancet.com) |
What they have demonstrated is preliminary safety of a possible vaccine through no severe adverse effects, and also that it did produce some type of immune system response.
Phase 2 trials will begin to determine the actual effectiveness of the vaccine.
> Before vaccination, 20 (56%) participants in the low dose group, 19 (53%) participants in the middle dose group, and 16 (44%) participants in the high dose group had a high pre-existing Ad5 neutralising antibody titre (>1:200). Only five (25%) participants of 20 in the low dose group, seven (37%) participants of 19 in the middle dose group, and ten (63%) participants of 16 in the high dose group, who had high pre-existing Ad5 immunity, had at least a four-fold increase in neutralising antibody titre at day 28 post-vaccination (appendix pp 8–10). Multivariable analysis showed that high pre-existing Ad5 neutralising antibody titres compromised the seroconversion of neutralising antibody post-vaccination, regardless of the vaccine doses, and recipients aged 45–60 years seemed to have lower seroconversion of neutralising antibody compared with the younger recipients (appendix p 11). The Ad5 neutralising antibodies were significantly boosted post-vaccination (appendix p 12).
It's good that they aren't expressing this like a "Eureka, we did it". At least we have one candidate. Let's see what else comes our way.
I think it's a safe bet that there will be multiple different vaccines. What you get will be determined by availability firstly, and safety profile if necessary. It's really no different from any of the medicines we already use. For example, the vast majority of antibiotics are manufactured in China; have you ever heard of someone turning down antibiotics because they were made in the wrong country?
Safe vaccines take years or decades. I personally get all my shots, but I'm not about to take a vaccine developed in two years! Especially if I'm not in the high risk group. I don't think it would be unreasonable for people to wait 5~10 years and see the effects of early adopters first.
Say, the United States votes Trump in for a 2nd term. And he goes on a media blitz to convince people to not take the China vaccine.
Meanwhile, the rest of the world takes it. The vaccine is ultimately successful, and Covid-19 is effectively eliminated.
What will happen to the United States? Will the virus continue to ravage the country and the economy? Meanwhile, the rest of the world begins their economic recovery.
Never could I imagine that this idea would even be a probability. But yet, here we are.
Why would he do that? He's in the pockets of big pharma. The president is pretty much a puppet. Both Biden and Trump will push any vaccine presented to them by the big pharma giants (Gavi/Gates/GSK/Bayer/etc.) because that's the base that supports them. Biden and Trump may promote different vaccines from different companies, but it's just depends on which one gets elected and which particular giants are backing that candidate.
Does that need to be hypothesized about? Of course he will win.
If you like your Chinese vaccine you can take your Chinese vaccine.
The more people want it, the less value it has for people not eager to take it.
I'm sure a SARS vaccine is a completely different animal, and I don't know enough about viruses to know how hard it is to make a safe coronavirus vaccine, but your objection seems to be entirely about the timeline.
SARS1 vaccines had some very troubling imunopathic responses and feline SARS1 vaccines made reinfections worse. This will be a totally new vaccine, for a virus family we've never developed vaccines for before, and some of the techniques they're using (the DNA/RNA technique pushed by Gavi/Gates) has never had a vaccine make it through a clinical trial before.
Those are the troubling things. I wrote more about it here:
https://battlepenguin.com/politics/this-is-not-a-time-of-hon...