You would need a provenly safe vaccine that we will not have within a timeframe of a few months and the threat from COVID probably doesn't justify a mandate. The severe reaction to it cannot be used as an argument here.

I think many adults would just refuse it with severe disadvantages for further medical exceptions because of lost trust. I believe people would have the right to just use the Swedish approach, which seems more sensible by the day. You can restrict travel to a degree for some countries, but not for a longer period of time.

> policymakers and the public will need to understand the limits of what is known

That includes the knowledge about a mandate being sensible or not and how policies can decide what risks people are willing to take.

> Public trust has already been compromised by federal officials’ endorsement of hydroxychloroquine as a Covid-19 treatment without evidentiary support

No, that wasn't a big issue. Be better about your judgement. For example:

> a generous compensation program for people who have serious vaccine side effects should be a centerpiece of these efforts.

This would make me more concerned about vaccines with insufficient testing...