Recent sales: Nyan Cat ($590K), Grumpy Cat ($100K), Overly Attached Girlfriend ($459K), Leave Britney Alone ($43K), Bad Luck Brian ($45K), Success Kid ($35K), Annoying Orange ($???)

Emergence of Uniswap (trading) and Arweave (cloud) services are also bullish indicators ;)

9GAG is worth half a billion dollars, according to a quick search.

RBLX is worth over 40 billion dollars.

Let's not forget all the people who bought GME because it was a meme.

Memes used as ads to sell products.