Peter Daszak, Peter Daszak's associates and funding partners, EcoHealth Alliance (EHA), and the Wuhan Institute of Virology (WIV) have all been in tight consensus that this line of manipulation is not of interest in investigation. It was bashed as a conspiracy theory without potential, and listed as a highly unlikely origin. With this leak, all of these statements are in dire conflict. The evidence in the leak shows there may be a severe conflict of interest in protecting themselves over a full scientific investigation.
Anthony Fauci made a very specific statement that it was "molecularly impossible" and thus improbable that the virus could have been created with manipulation instead of nature. I'm giving Fauci the benefit of the doubt at the moment since government officials might be expected play dumb on secrete DARPA proposals, but his statement is none-the-less inaccurate based on the leak. There is probability to create a similar virus to COVID-19 with manipulation.