Hi. Sure.
The experience is extremely similar to the traditional/original Server Side Rendering model; that is, sending back HTML to the user agent. Where that traditional model was much too limited, by only allowing full page refreshes and only two elements that could do server interaction (<a> and <form>), HTMX is completely robust.
HTMX allows you as the developer to fire a server side request from ANY HTML element for all the HTTP METHODS (GET, DELETE, POST, PUT etc.). In addition, you decide and design what HTML fragment you will return from the server and where it should be swapped into in the browser's page. So instead of full page refreshed, you are surgically updating anywhere in the DOM quickly - very quickly.
I want to be clear, you, as a developer, are thinking this model and flow FROM THE SERVER SIDE of things. You are returning fragments or chunks of HTML as the response, NOT JSON. With all things in technology, obviously, there are trade-offs, but eliminating the JSON layer and the client code layer, you are eliminating a massive class of complication.
Also, I would like to stress, that this does sound very similar to jQuery and other things like that, but it is pretty different and better IMO because it is coded as attributes in the element tags. As they say on their site, it truly feels like this is what HTML would have felt like if it was continued and completed, instead of veering off into heavy use JavaScript land like we did as an industry.
There are many nice little features to add to the dynamic feel of your web apps, such as in progress indicators and CSS animations; again all specified as attributes in the tags.
Finally, the development environment is basically a non-existent complication. It is a tiny (~12k) js file and <script> inclusion. You choose any traditional SSR library for your language of choice. HTMX can actually breathe life back into server side languages, where instead of writing monotonous and boring end-points attempting to be some sort of data access layer, you are writing fully robust code, and you have full power and access to your real data layers.
Yikes hope that wasn't too verbose and answered your question ;) But I really love HTMX after so many years of what I have considered toiling with web UIs. Hypermedia is supposed to be the ultimate thin client model as termed by HATEAOS, not insanely rich clients trying to emulate client server interactions through REST API IMHO.