Ketones Reverse Brain Aging During Midlife Critical Window

Ketones Reverse Brain Aging During Midlife Critical Window(pnas.org)

19 points by rhodescolossus 1 year ago | 9 comments

thadk 1 year ago |

Been on the diet for most of 30’s. The benefits can be great if you can eat real food and keep up the electrolytes too. There is just no safety margin left in the body if you can’t satisfy metabolic needs on the intense diet for a few days, and don’t want to drop it, which has its own flu-like costs. The author’s trial could hold a solution: keep the insulin safety margin while supplementing the helpful ketones.

Then my question, what are the standards involved in producing the ketones to keep them safe?

metalman 1 year ago | |

a good diet to get good results is like horseshoes or handgrenades, close is good enough drop 99% of the grains and ultra proced foods, go big on fats and cheese,fruit,raw vegatables, stay as low on the gycymic index as you can, avoid shugar like the fucking plague, and artificial nothing and no booze....it's called the food diet, made from food, no caned,jared, or bottled.....stuff, eat the food, be happy and well work your ass off, lots of personal care there are no goals or objectives,there is zero down side possible, its a sense of momentum, staying in the groove,keeping your mojo working ;) Stop and accept this(RTFM) a very large chunk of your body was built and designed to get and process food,externaly and internaly, like more than 50% of your mass is devoted to this, so

mixmastamyk 1 year ago |

Kinda hard to read but seems to support the idea that a keto diet helps keep the brain sharp as we age.

Also learned that “keytone supplements” are a thing to kickstart the process. Looked into, they appear to be very expensive for common organic chemicals. Cutting most carbs from the diet should be a lot cheaper.

JanisErdmanis 1 year ago | |

Endurance sports and fasting are also a viable alternatives to a strict keto diet which are cheaper to do.

snvzz 1 year ago | |

Even cheaper is to stop eating.

That switches body to keto in a matter of hours.

euroderf 1 year ago | | |

There must be a reason in here somewhere to switch from beer to wine.

snvzz 1 year ago |

Or, same thing, carbs prevent reversing of brain aging during midlife critical window.

It always comes down to carbs (incl. sugar) bad.

Intermittent fasting is a must. Otherwise, body simply runs on carbs non-stop.

ninininino 1 year ago |

I pasted the study into ChatGPT and asked it if the study is saying we need to take on a ketogenic diet to get the benefit or just take a supplement, and it suggested that just taking a supplement (exogenous ketones) in particular D beta-hydroxybutyrate ( D-βHB ) is enough. And that the benefit occurs during the years of 40-60 but that past 60 the window to benefit may have passed.

ozgrakkurt 1 year ago | |

This perfectly showcases why chatbots are literally useless 90% of the time. It is not possible to verify this without reading unless I know the subject very well and I don’t need the chatbot if I know the subject that well anyways