It's a cool idea but it kind of bothers me that with all this effort, you still only get a boolean worth of information (it was either accessed or not). No clue about who, when, where or why.
there is I believ a similar thing useing paint spatters as idicators of authentisity of electronics and also as proof of tampering, as the patterns are unique and can be produced, recorded ,quickly and cheeply.
> If of one or more elements within the mosaic are modified, unauthorized access or compromise can be assumed.
... But how is the recipient certain of what the mosaic should be? You can't put the reference photo in the same package, because it's taken after sealing. And if you send it separately, that package is also subject to tampering.
> ...an original photo, which has been taken for example, by a manufacturer, signed and transmitted to a customer via an encrypted communication channel, with a photo of the current state.