What Do We Know About the Microplastics Inside Us?(e360.yale.edu) |
What Do We Know About the Microplastics Inside Us?(e360.yale.edu) |
A friend of mine worked on her bachelor’s thesis about the effects of microplastics on the immune system, specifically T cells. Her result was that the microplastic particles she studied were too large to interact with T cells.
She probably will not publish this result because she thinks it is not interesting enough. Classic file-drawer problem in academic science.
While I encourage her to do it anyways as a negative results is also interesting but she wanted results that are worthing of headlines in magazines.
It's truly insane that everyone in the academic class understands the fundamental problems of herding and sampling bias and yet every incentive is in place to do this.
Yeah, but we shouldn't take absence of evidence as evidence of absence. The fact is that it's just really really hard to establish a causal relationship, even if it's there, because of all the cofounders. Heck even if you constructed a study with a known poison, like lead, and you might not see the results in a single study. You could give 50 participants water with flint levels of lead in it for a month, and you might not get scientifically significant result just due to the wide variance in a population.
Or another example is just thinking how hard it would be construct a study with a control, when every single construction material has plastics in it and they are floating in the air around us all the time (as mentioned in the article). Could it affect mental or reproductive wellbeing? Certainly. Can we construct a study to establish either way? Not easily.
And one of the plasticizers they talk about, pthalates, are known to be endocrine disruptors (i.e. mess with hormones).
That's wrong. Yes, we should.
Each and every study that doesn't find evidence for what they are looking for is evidence for its absence.
Learned a lot about making microfludic flow cells at least
Also, unfortunately, a result that industry and the anti-regulation crowd will use to say microplastics are harmless.
Her "result" of what? Was there an actual experiment and what was its scope or was this by surveying literature?
Microplastics are of a pretty large range of size, and then there are nanoplastics below that.
I'm also not an expert, but a quick search shows a number of results of microplastics affecting T cells, some directly and some in terms of immune signaling, so this negative result doesn't seem that definitive.
(as usual, the difficulty is in teasing out in vivo effects)
Very informative, thank you for your comment. You have truly contributed to the conversation. Good job.
As far as I am aware, we have yet to have effective, replicable research on what if any biointeractions exist with nanoplastic particles, including single polymer chains.
>https://www.eurekalert.org/news-releases/923529
But your linked study only talks about biofilms and E.coli?
> We assessed how reliable current measures are for trying to find microplastics in blood. And what we found is that lipids and fats will give you a false positive for polyethylene.
> We worked with an architect, and we built the lab pretty much from scratch. [...] So we ended up going with stainless steel. It was the only way to not have any plastics.
> I don’t think we’ve got really good evidence at all for what effects [microplastics particles on their own] might be having on human bodies. If we’re eating plastics, what size and what type of plastic can actually get into the bloodstream?
Words have meaning.
Upwardly mobile middle/upper class people who've sort of "maxed out" the amount of personal identity they can buy with regular plastic things can unlock a new level of identity by deciding that plastics are bad for them and eliminating plastics from their life, a process which conveniently requires buying a whole new set of things that distinguish them from their peers.
This is the only way I can explain how irrational and inconsistent plastic-haters behavior is. There is so much invisible plastic in their life that they don't seem to care about.
Getting to the point where we're actually able to measure something real is good progress.
and >...we found is that lipids and fats will give you a false positive for polyethylene. Lipids are made up of the same building blocks as polyethylene, so when we analyze them, they look identical in our analysis instrument. >I know it is easy to say we don’t have enough information yet, but we do know about [the health risks from] these chemicals that are in all the plastics that your food is wrapped in.
> And while we know a lot about the impact of chemicals added to plastic — such as phthalates, which have been shown to impact fertility, or bisphenols, which have been linked to Type 2 diabetes — we know very little about what effect the plastic particles themselves might be having.
Silicone holds the glass panel. Silicon is the glass itself. Yale editors, do your job. She worked "a crazy amount of details", and so can you!
No, it requires buying a whole new set of things to fit in with and be accepted by their peers, to distinguish themselves from the outgroup, the plastic users.
I don’t necessarily believe this is some emergent elitism; I see it more as a modern religion with many many rules about eating and consumption (using plastic is now a sin).
Like any religion, sinners (for example plastic users) are mostly pitied because they are ignorant, but those who know and choose to use plastic anyway, well, it’s OK to hate them.
I think the fact that I volunteer to clean up trash on public lands and know that weathered plastic is the period worst period to remove makes me move away from plastic in general.
Plus, a solid $3 wooden spoon is just a joy to cook with. They outlast the plastic ones, too.
Microplastic ingestion? Well, I'm not sure the effects or the relative quantity compared to tire shed and other industrial factors. But if I were forced by some diety to bet my life on if plastics in the kitchen or on clothing had a negative health effect, I'd make that bet.
But the main thing I don't get about the attitude stems from the fact that I don't really care what other people use in their kitchens. I recommend it.
Just please don't litter. :)
1. Is it based on inherently irrational, unfactual beliefs, e.g. like anti-vaccination or anti-5G myths?
2. If we consider religion as a way to explain complex phenomena using just-so stories (the pop anthropology / layman idea of primitive man inventing Zeus to explain lightning), then what intellectual or emotional need does anti-microplastics belief validate?
Most of human behavior is irrational. If we were all perfectly rational, we would have healthy diet and exercise habits from the get go, and we'd have plenty of time to prepare food and exercise, because we wouldn't waste any time on entertainment.
Isn't this almost true by definition? If it actually works, it's not a "fad", just "science" or whatever. Advice like "eat more vegetables" and "don't drink alcohol" probably do work, but they're ingrained enough that nobody thinks they're "fads".
Anything that shows evidence of omnipresence, endocrine disruption, bioaccumulation, and inter-generational transmission should be extremely, extremely closely scrutinized.
To think otherwise is absolute braindead contrarianism, full-stop.
Huh? You think it's hypocritical for people not to "seem to care about" things that, by your own definition, they are ignorant of?
The mechanism of harm for asbestos is known to be that the fibers enter the lungs and can't be expelled, eventually leading to cancer. Its interaction with T-cells is quite irrelevant there.
Careful, you're starting to sound dangerously close to an Austrian economist!
[ ;) ]
The reason this is problem is because cells can never destroy nano-plastic so they keep self destroying forever (chronic inflammation).
I still have my doubts about actual scale of this, especially how we still haven't solved pm2.5 pollution or even asbestos and heavy metals. And then there's PFAS, VOCs, Phthalates and Bisphenols. There's insane amounts of benzene in gas stations and traffic jam, yet no one really gives a fuck (until there's like a ppm in a sunscreen lol).
You are most likely to inhale it due to plastic abundance in environment, just like thousands of other things. It doesn't even have ICD yet. Ingested microplastic unlikely to breakdown while it travels thru your body.
p.s. my partner de-plastified a lot of my life (thru a lot of opposition of me) to the point where a lot of plastic objects feel gross now.
Right, and when it comes to "what happens when the macrophage can't destroy what it engulfed", we can probably learn a lot from parallel work studying tattoos, where the ink-particles are similarly "attacked".
Plus it's a lot easier to create studies or even just observe the cells in question.
If the studies are powerful enough then that absolutely isn’t evidence of absence at all.
Of course it's still possible for the theory to be wrong and the so-called junk DNA being actually important. It's only junk according to our classical, non-quantum and non-relativistic theory of junkiness.
And on the topic of cost, I'm certain my kids have broken between 50 and 100 glass and ceramic drinking cups, storage containers, plates, and bowls in a little over a decade. They destroy plastic items at a way, way lower rate. Consider the use case of packing a kid's lunchbox. Plastic is... very tempting, for practical reasons. And cheaper.
Last I checked, plastic vs. wood on an otherwise identical stamped metal Victoronix knife costs you an extra $15-$20, which is a notable percentage of the total cost of the item. I sprung for the wood on my latest replacement just for the aesthetics, but it cost enough more that I did give it a good think first.
> Even bamboo scrubbers don't cost more than plastic (maybe even a little less) and I can't see any particular longevity difference.
Are those actually just bamboo? Maybe they are, I dunno, I can't recall seeing one. Lots of the "bamboo" materials I've encountered have turned out to contain (at least some) plastic.
> Plus, a solid $3 wooden spoon is just a joy to cook with. They outlast the plastic ones, too.
That's just true. Plastic spoons for cooking suck, wood and (where it makes sense and won't damage other things) metal are way better. Wooden ones aren't even expensive. The popularity of plastic ones is baffling.
One thing that's surprised me is the cost and/or total lack of availability of glass blender jars, even on fairly high-end brands (both the fake-high-end ones that are just expensive, and the actually-good ones). I remember my parents' assuredly cheapest-thing-in-the-store blender that they probably bought in the 70s or 80s had a glass jar, because that was just... standard. Meanwhile my as-awesome-as-I'd-hoped-thank-god expensive-ass Vitamix came with a plastic jar, and they do not make glass replacements. (I'm just checking and it looks like they might finally make one in stainless, though? Still, I'd prefer glass because being able to see what's going on in there is very nice, but I'm gonna have to look into that...)
> That's just true. Plastic spoons for cooking suck, wood and (where it makes sense and won't damage other things) metal are way better.
If you have ever used nice commercial high-temp silicone spatula, it's an incredibly versatile and easy to clean spoon for cooking. A bit expensive at like $20 though. Pair with nice nonstick pan and polycarbonate cutting board (dishwashable) for the easiest and most out of fashion cooking and cleaning experience.
> One thing that's surprised me is the cost and/or total lack of availability of glass blender jars
My cheapest in the store oyster blender is glass, I think they mostly still are.
Those, I do use! My wife insists on keeping one non-stick pan, mostly for eggs (I just cook them in stainless, whatever) so we've got a couple around for that specific use case, but I grab them sometimes for other things, too. They're great for scraping little bits of sauce out of the edge of a pan, things like that.
> My cheapest in the store oyster blender is glass, I think they mostly still are.
Ha! Really? I killed one blender before upgrading (the old "buy a cheap one, and if you wear out out, buy the expensive one" approach) and that was also plastic, but it probably wasn't Oyster. Hm.
All of those were glass when I was a kid, it seems really weird to me that the pricey ones are usually plastic now. I'm not even (that) worried about the health effects of it, I mostly just like the way the contents move & pour in glass better, the plastic's too "sticky" (though I do cringe a little when we blend a near-boiling sauce in the plastic jar)
There is practically nothing that ordinary people can do for prevention, mitigation, diagnosis or treatment of microplastics in our bodies, so I therefore conclude that it is futile and wasteful to worry or argue about it, unless you have abundant free time and resources to get paranoid strangers all in a frenzy, for no good reason.
Like I'm pretty sure the bigger health risk with a plastic soda straw is the soda, not the straw, you know?
What about those advocating for smoking bans in shared spaces?
Cholera outbreaks near the city water wells?
Or are microplastics special in some way?
Discover what plastic is harmful and we can't start to talk.