Several chorded keyboards came to market in the UK, receiving plenty of press (eg coverage on an influential weekly TV technology magazine program, in the days when there were only a handful of broadcast channels). They all failed dismally despite attracting a small core of devoted fans.

You can get highly customizable mice with multiple programmable buttons etc. Only gamers buy them. I do edit video and audio for work and while I like my key combos as much as the next person and sometimes set up hardware mappings on external devices for big jobs, I don't think any of them need to be universal.